{"id":38757,"date":"2024-01-06T07:55:22","date_gmt":"2024-01-06T06:55:22","guid":{"rendered":"https:\/\/www.myspecialdoctor.it\/uncategorized\/paracetamol-abuse\/"},"modified":"2024-02-08T17:58:03","modified_gmt":"2024-02-08T16:58:03","slug":"paracetamol-abuse","status":"publish","type":"post","link":"https:\/\/www.myspecialdoctor.it\/en\/editorials\/paracetamol-abuse\/","title":{"rendered":"Paracetamol abuse"},"content":{"rendered":"<p><strong>Paracetamol <\/strong>is mainly used as an analgesic as an alternative to salicylates and is characterized by toxicity, which should not be overlooked. <strong>Toxic doses <\/strong>vary from person to person, so many have determined that the amount needed to induce liver damage is 15 grams, while the fatal risk requires 25 grams.<\/p><p>During the first day, <strong>symptoms <\/strong>are nonspecific: pallor, vomiting, nausea, and sweating. Then liver damage appears, eventually progressing to hepatomegaly, jaundice, hypoglycemia, and encephalopathy.<\/p><h3 class=\"wp-block-heading\">What are the principles of therapy?<\/h3><ul class=\"wp-block-list\"><li>Induction of vomiting, gastric lavage and activated charcoal if action is taken within 6 hours of ingestion.<\/li><li>Methionine, specific antidote or N-acetyl-cysteine<\/li><li>Silymarin<\/li><li>Vitamin K<\/li><\/ul><p>Source: Medical Guard Handbook edited by Piercarlo Salari (Mediserve)<\/p>","protected":false},"excerpt":{"rendered":"<p>Paracetamol is mainly used as an analgesic as an alternative to salicylates and is characterized by toxicity, which should not &#8230; <a title=\"Paracetamol abuse\" class=\"read-more\" href=\"https:\/\/www.myspecialdoctor.it\/en\/editorials\/paracetamol-abuse\/\" aria-label=\"Read more about Paracetamol abuse\">Read more<\/a><\/p>\n","protected":false},"author":8782,"featured_media":22839,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","pmpro_default_level":0,"footnotes":"","_wpscppro_custom_social_share_image":0,"_facebook_share_type":"","_twitter_share_type":"","_linkedin_share_type":"","_pinterest_share_type":"","_linkedin_share_type_page":"","_instagram_share_type":"","_medium_share_type":"","_threads_share_type":"","_selected_social_profile":[]},"categories":[1749],"tags":[2093,2221,2278],"corpo":[1761],"table_tags":[],"class_list":["post-38757","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-editorials","tag-poison","tag-poisoning","tag-pracetamol","corpo-respiratory-system","pmpro-has-access"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/posts\/38757"}],"collection":[{"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/users\/8782"}],"replies":[{"embeddable":true,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/comments?post=38757"}],"version-history":[{"count":3,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/posts\/38757\/revisions"}],"predecessor-version":[{"id":40914,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/posts\/38757\/revisions\/40914"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/media\/22839"}],"wp:attachment":[{"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/media?parent=38757"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/categories?post=38757"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/tags?post=38757"},{"taxonomy":"corpo","embeddable":true,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/corpo?post=38757"},{"taxonomy":"table_tags","embeddable":true,"href":"https:\/\/www.myspecialdoctor.it\/en\/wp-json\/wp\/v2\/table_tags?post=38757"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}