Herpes simplex viruses (human herpes virus types 1 and 2, HHV-1 and 2) commonly cause a relapsing infection affecting skin, mouth, lips, eyes, and genitalia. Common serious variants include encephalitis, meningitis, neonatal herpes, and disseminated infections in immunocompromised patients. Mucocutaneous infections manifest as clusters of small, painful, erythematous-based blisters. Diagnosis is clinical; laboratory confirmation can be obtained through culture tests, PCR (polymerase chain reaction), direct immunofluorescence, or serologic tests. Therapy is symptomatic; antiviral treatment with acyclovir, valacyclovir, or famciclovir is useful in severe infections and, if started early, in primary or recurrent infections.
New method for aortic valve replacement
New method to perform aortic valve replacement proves effective in high-risk patients. The findings may increase less invasive treatment options for patients with life-threatening heart disease. A new, less invasive
