ARTICOLI CORRELATI

Infectious diseases: tetanus

Tetanus is an acute noncontagious infectious disease caused by the bacterium Clostridium tetani. It is a Gram-positive bacillus that grows only in the absence of oxygen (i.e., it is anaerobic),

Exposure to chemicals

A corrosive substance can damage tissue within minutes, so it is very important to remove it quickly. What to do? First, immediately call for an ambulance. If the chemical remains

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In the tranquility of our kitchen we may inadvertently incur a sunburn. We almost always immediately resort to the traditional methods passed down from our parents. Be careful, however, these

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Among the most insidious and widespread skin diseases is certainly Melanoma, a skin cancer that has grown significantly in recent decades but whose etiology remains poorly understood to date.

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Many diseases can cause abdominal pain, but some conditions can be life-threatening and therefore require surgical treatment. What to do? It is necessary for the victim not to eat or

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Angina pectoris expresses myocardial ischemia, and its diagnosis is based primarily on the evaluation of patient-reported complaints. Angina can be related to exercise. There can be many different causes: it

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What is hemoperfusion?

emoperfusione

This is a system in which blood is brought from the patient, by arterial cannulation, into an extracorporeal circuit. The blood, before returning to the body via the venous route, is cleansed of toxins. Nonionic resins and activated charcoal in granular form are used to perform hemoperfusion .

Just as with hemodialysis, hemoperfusion does not can speak of a universal answer to all problems facing the clinician toxicology. It should be limited only in certain cases:

  • The adsorbent has an affinity for the toxin
  • The amount of circulating toxin must be a good portion of that contained in the body
  • There is a correlation between the concentration plasma toxin and the intensity of poisoning.

Hemoperfusion is contraindicated when:

  • The toxin has a large volume of distribution
  • The natural metabolic inactivation of the toxin is able to proceed faster than the time it takes for staff to health care to proceed with hemoperfusion
  • The toxic mechanism is precise and quick.

Hemoperfusion is, therefore, indicated, when:

  • No other methods of treatment
  • The toxin that threatens the patient has a small volume of distribution in the body
  • The substance has been analytically identified in the blood.

Techniques

Performing a hemoperfusion requires the cooperation of experienced people, as it requires the same degree of experience that is needed for hemodialysis. Facilities must be available to measure drug concentration in the palsma so that electrolyte balance, heparin levels, and other hematologic parameters can be repeatedly checked.

A fall in leukocyte and blood platelet values is possible. Random bleeding can be worrisome and even disastrous, so even minor surgeries should be performed with caution.

Source: Roy Goulding’s Vademecum of Poisoning Therapy.

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