of

Between the digestive system and the immune system: the gut in the early ages of life

offal-1463369_1280-2

The bowel, anyone would say, is the body in charge of the digestion and assimilation: its conformation to tube and its motility, in fact, enable it, thanks to enzymes, to break down ingested foods into their individual components (so-called nutrients), absorb them into the circulatory stream, and finally “push” unusable food residues so that they are eliminated in the form of feces.

The gut as an immune organ

Nothing to object to except for the fact that in this cursory overview another function no less important than those described has been omitted: the gut, in fact, is also an immune organ whose task is crucial in the early ages of life. Let us reflect for a moment: the absorbent mucosa, which in the adult individual has an area of as much as 400 square meters, can be considered on a par with the skin. Similarly to it, in fact, although it constitutes the inner lining of the intestine, it is constantly in contact with what comes from outside and thus plays a role as both a sentinel and a barrier.

The wall of the intestine, on the other hand, is rich not only in blood vessels, which receive nutrients and distribute them to all tissues of the body, but also in lymph vessels, where lymphocytes circulate. In fact, these particular highly specialized white blood cells, after forming in the bone marrow, need to be “trained” to perform their defensive task and find precisely in the digestive tract the optimal site for their break-in, also thanks to the presence of the bacterial flora.

A protection for the little ones

In the young child, then, let us not forget that the introduction of any new food is perceived as a potential aggression. In practice, the immune system cannot distinguish between a virus and a food protein, but thanks to special systems it develops what is known as tolerance: that is, it suppresses the mechanism by which contact with various foods would trigger the reaction underlying intolerance, namely the allergic response.

FEATURED SPECIALISTS

  • Profile picture of Dr. Giovanni Arrichiello
    active 5 years, 8 months ago

    Gynecologists, Basic Doctors

    • Corso Regina Margherita 260 - Torino
    phone
  • Profile picture of Dott.ssa Ilaria Berto
    active 5 years, 8 months ago

    Basic Doctors, Acupuncturists, Aesthetic Doctors

    • Via Antonio Corradini 1 - Este
    phone
  • Profile picture of Dott.ssa Federica Filigheddu
    active 5 years, 8 months ago

    Basic Doctors

    phone
  • Profile picture of Dott.ssa Maria Grazia Caruana
    active 5 years, 8 months ago

    Aesthetic Doctors, Basic Doctors

    • Viale Prassilla 41 - Roma
    phone
  • Profile picture of Dr. Lucia Catalano
    active 5 years, 8 months ago

    Gynecologists, Senologists, Basic Doctors

    • Via Belluno 1 - Roma
    phone

RELATED ARTICLES

Acute hemiplegia in children

Symptoms of acute hemiplegia may be hemianesthesia, hemianopsia and aphasia. The onset of symptoms is sudden and peaks within a few hours. The onset of hemiplegia may be preceded or

What is plateletopenia?

The plateletopenia is the condition in which the number of platelets is lower to 150,000 mmc. This can occur due to reduced production, from sequestration or by an increase in

Bronchial asthma in children

Asthma bronchial is due to mucosal edema and stagnation of sputum. To evaluate the severity of asthma it is necessary to reconstruct the patient’s life through previous hospitalizations, feeding and

Pregnancy and the mother-child dyad

This course examines the individual's line of development beginning with pregnancy and how alterations in it can lead to mental pathology in childhood, adolescence, or adulthood.

What is hematemesis?

Hematemesis is the oral emission of blood with vomiting. Symptomatology and objective signs depend on etiology. In the case of massive hemorrhage, symptomatology and objectivity in hypovolemic shock will be

RELATED PATHOLOGIES

Celiac disease

Celiac disease is an autoimmune disease that can occur in genetically predisposed people in whom the ingestion of gluten results in damage to the small intestine. It is estimated to

Colon cancer

Colorectal carcinoma is the malignancy that most frequently affects the colon, rectum, and appendix. It is the third most common form of cancer in the world. It is characterized by

Diverticulitis

Diverticula are small pockets that can form in the lining of the digestive system. They usually occur more frequently in the lower part of thelarge intestine (colon). Diverticula are common,

Intestinal polyposis

Polyps are abnormal growths of tissue protruding to a mucous tonaca; they are pathological growths that, in the intestines, form especially in the colon and rectum. For the most part,

Dyspepsia

Dyspepsia means “difficult digestion” and is the medical term often used to refer to indigestion, which instead has a more general meaning and encompasses a multitude of different disorders of

Gastroesophageal reflux

Gastroesophageal reflux disease (GERD) consists of a pronounced rise of some of the acidic contents of the stomach back up into the esophagus, promoted by a poor seal or increased

Esophagitis

Esophagitis is an acute or chronic inflammation that can damage the tissues of the esophagus, the stretch of the alimentary canal that connects the pharynx to the stomach. In mild

Barrett’s Esophagus

Barrett’s esophagus is a serious complication of gastroesophageal reflux disease. In Barrett’s esophagus, the normal tissue lining the esophagus-the tube that carries food from the mouth to the stomach-is transformed

Malabsorption syndrome

The role of the small intestine is to complete the chemical breakdown of food and to absorb almost all nutrients. Malabsorption syndromes are a group of conditions united by the

Liver cancer

Several types of tumors can form in the liver. The most common type of liver cancer is hepatocellular carcinoma, which begins in hepatocytes, the main type of liver cells. Other

FEATURED SPECIALISTS

  • Profile picture of Dott.ssa Floriana Di Martino
    active 5 years, 8 months ago

    Aesthetic Doctors, Basic Doctors

    • Piazza della Rinascita 13 - Pescara
    phone
  • Profile picture of Dr. Sergio Ettore Salteri
    active 5 years, 8 months ago

    Basic Doctors, Chiropractors, Posturologists

    • Via Vial di Romans 8 - Cordenons
    phone
  • Profile picture of Dott. Gianlorenzo Casani
    active 5 years, 8 months ago

    Geriatrics, Certifying Doctor, Basic Doctors

    • Via Costantino Baroni 71/73 - Milano
    phone
  • Profile picture of Dott.ssa Ilaria Berto
    active 5 years, 8 months ago

    Basic Doctors, Acupuncturists, Aesthetic Doctors

    • Via Antonio Corradini 1 - Este
    phone
  • Profile picture of Dr. Virgilio De Bono
    active 5 years, 8 months ago

    Aesthetic Doctors, Basic Doctors, Dermatologists

    • Via Ripense 4 - Roma
    phone

prenota il tuo viedeoconsulto in convenzione

Completa il form e sarai contatto dal personale medico specializzato

your advertising
exclusively ON
MY SPECIAL DOCTOR

complete the form and you will be contacted by one of our managers