ARTICOLI CORRELATI

Eating disorders: dyspepsia

Digestion is an essential process for the life of humans and many other living organisms. Feeding is not just an instinct, but a pleasure, an indispensable ritual aimed at socialization

The empowerment of the diabetic patient

When we talk about empowerment, we are basically talking about a slow and progressive process of health literacy, that is, an action of spreading a social concept of health, where all people have the right, but also the duty, to be well informed about health issues and the diseases that affect them.

Assessment of nutrition status

Both the medical history and the objective examination are essential for the assessment of nutrition status. It is very important to collect information on nonprescribed weight changes, adequacy of energy

Childhood obesity: two “household” risks

Sitting for too long in front of a computer screen, TV, smartphone or tablet or playing playstation, especially with a high-calorie snack in hand, puts children and adolescents’ fitness and

Bacterial infections and international travel

Having to undertake a trip, whether for business or leisure, it is necessary to gather detailed information about the places one intends to visit, considering the map of countries where the risk of exposure to "traveler's diseases" is highest.

High Cholesterol? A new strategy on how to lower cholesterol

How to lower high cholesterol

There are several drugs that can lower cholesterol (cholesterol values), one of the key factors in heart health. Chief among these are statins. However, a group of specialists has identified ezetimibe, a drug that has been on the market for years, as particularly effective not only in combination with statins, but also when used alone. Indeed, ezetimibe reduces intestinal absorption of cholesterol and, consequently, also plasma levels of ‘bad’ cholesterol (C-LDL), with a good tolerability profile.

So-called “high cholesterol” is a major challenge for physicians today, especially in patients at high cardiovascular risk and in cases where first-choice treatment with statins is not well tolerated or does not achieve guideline-recommended cholesterol levels. Indeed, let us not forget that hypercholesterolemia is a direct cause of cardiovascular disease, which in Italy alone is responsible for more than 200,000 deaths a year, including 70,000 from ischemic heart disease, including heart attack, the most feared.

According to specialists, ezetimibe is particularly effective in decreasing the risk of adverse cardiovascular events, even in patients who have already experienced some cardiovascular complication: unlike statins, which have a direct action on cholesterol production, ezetimibe inhibits the absorption of cholesterol in the intestine. The combined use of both drugs – statins and ezetimibe – makes it possible to achieve the so-called “double blockade,” which is especially indicated for certain categories of patients, for example, diabetics, in whom intestinal cholesterol absorption is rather high.

Although statins are relatively safe for most patients, they can sometimes induce side effects, including serious ones. Numerous clinical studies show, in fact, that 30 percent of patients on statin therapy may develop significant adverse reactions such as myalgias, myositis, hepatopathy and headache, making it impossible to continue treatment. In contrast, ezetimibe, due to its unique mechanism of action, has no significant interactions with other
drugs and is extremely tolerable both hepatically and muscularly.

Therefore, ezetimibe is a viable alternative for all those patients who are contraindicated from using statins.

SPECIALISTI IN EVIDENZA

  • Profile picture of Dott.ssa Carmela Tizziani
    active 3 years, 9 months ago

    Coroner, Certifying Doctor, Basic Doctors

    • Via Gaetano Bruno 25 - Napoli
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    active 3 years, 9 months ago

    Psychotherapists, Basic Doctors

    • Via Sacconi 1 - Borgonovo Val Tidone
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  • Profile picture of Dott. Gianlorenzo Casani
    active 3 years, 9 months ago

    Geriatrics, Certifying Doctor, Basic Doctors

    • Via Costantino Baroni 71/73 - Milano
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  • Profile picture of Dott.ssa Ilaria Berto
    active 3 years, 9 months ago

    Basic Doctors, Acupuncturists, Aesthetic Doctors

    • Via Antonio Corradini 1 - Este
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  • Profile picture of Dr. Domenico D'Angelo
    active 3 years, 9 months ago

    Otolaryngologists, Basic Doctors, Competent Doctor

    • Via Pola 5 - San Prisco
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